Jen is Professor and Vice Chair in the Department of Genetic and Cellular Medicine, and Associate Director of the Horae Gene Therapy Center at the University of Massachusetts Chan Medical School in the U.S. Jen completed her B.S. degree in Chemistry at Youngstown State University, and her Ph.D. degree in Genetics and Cell Biology at Washington State University. After a post-doctoral fellowship at the National Institute for Environmental Health Sciences, Jen studied gene therapy at Fred Hutch becoming faculty in 2014. In 2020, Jen was named the Fleischauer Family Endowed Chair in Gene Therapy Translation. In 2025, she joined the faculty at UMass Chan to co-lead the first academic department focused on gene therapy translation. Her laboratory develops tools and methods for safe and effective delivery of gene therapy. Jen co-founded the Global Gene Therapy Initiative with Dr. Cissy Kityo in 2020.