Dr David Archer
Dr Archer’s research interests are in the pathogenesis and treatment of sickle cell disease. He has focused on the use of murine models of sickle cell disease examine disease process in multiple systems generating collaborations to address problems within sickle cell including sickle lung disease/pulmonary hypertension, sickle bone disease, sickle nephropathy, endothelial dysfunction and atherosclerosis, stroke and neurocognition, sickle hepatopathy, and the role of complement and innate immune mechanisms. Current studies are helping to investigate the mechanisms underlying poor pregnancy outcomes in sickle cell disease. His work has also focused on preclinical drug development working with Pharma and using a novel drug discovery program to generate and test novel therapeutics for sickle cell disease.